The Revenge of the Real envisions a new positive biopolitics that recognizes that governance is literally a matter of life and death. We are grappling with multiple interconnected dilemmas—climate change, pandemics, the tensions between the individual and society—all of which have to be addressed on a planetary scale. Even when separated, we are still enmeshed. Can the world govern itself differently? What models and philosophies are needed? Bratton argues that instead of thinking of biotechnologies as something imposed on society, we must see them as essential to a politics of infrastructure, knowledge, and direct intervention. In this way, we can build a society based on a new rationality of inclusion, care, and prevention.